Case report of a 3-year-old girl with pleuropulmonary blastoma and family history of a tumor predisposition syndrome with c. 2830 gene mutation in DICER1
نویسندگان
چکیده
منابع مشابه
Imaging findings in a 3-year-old girl with type III pleuropulmonary blastoma.
Pleuropulmonary blastoma (PPB) is a rare dysembryonic intrathoracic neoplasm in children. It is a malignant tumour originating from the mesenchyme with a poor prognosis. We report on a 3-year-old girl who presented with respiratory symptoms and was diagnosed as having a type III PPB according to histological results attained by open biopsy. Imaging by CT and MRI revealed the exact size of the t...
متن کاملConservative Management of Duodenal Perforation with Toothpick in a 9- Year Old Girl; a Case Report
Background Foreign body ingestion is a relatively common in children. Most ingested foreign bodies spontaneously pass out of the body via the gastrointestinal (GI) system but sharp materials may perforate the GI tract and need to surgical intervention. Case Presentation The patient was a 9-year-old girl with progressive abdominal pain for one month and admitted with acute abdomen impression. S...
متن کاملCalcifying epithelial odontogenic (Pindborg) tumor involving a 16-year-old girl with no prominent clinical manifestation: A case report
BACKGROUND AND AIM: The calcifying epithelial odontogenic tumor (CEOT) is a rare entity described by Pindborg and represents < 1% of all odontogenic tumors. Nearly 200 cases of this neoplasm have been reported to date. It mostly occurs in the posterior mandible associated with an impacted tooth, most often a mandibular molar. Patients are usually between 30 and 50 years of age, with no sex pred...
متن کاملBiallelic DICER1 mutations in sporadic pleuropulmonary blastoma.
Pleuropulmonary blastoma (PPB) is a rare pediatric malignancy whose pathogens are poorly understood. Recent reports suggest that germline mutations in the microRNA-processing enzyme DICER1 may contribute to PPB development. To investigate the genetic basis of this cancer, we performed whole-exome sequencing or targeted deep sequencing of multiple cases of PPB. We found biallelic DICER1 mutation...
متن کاملa comparison of teachers and supervisors, with respect to teacher efficacy and reflection
supervisors play an undeniable role in training teachers, before starting their professional experience by preparing them, at the initial years of their teaching by checking their work within the proper framework, and later on during their teaching by assessing their progress. but surprisingly, exploring their attributes, professional demands, and qualifications has remained a neglected theme i...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pediatric Surgery Case Reports
سال: 2015
ISSN: 2213-5766
DOI: 10.1016/j.epsc.2015.06.004